XENICAL is a prescription weight-control medication useful for the long-term treatment of significant obesity.
XENICAL can also help to improve risk factors, such as high blood pressure, high cholesterol and high blood sugar which, if not treated, could lead to other diseases such as hypertension and diabetes. Each XENICAL® capsule contains 120 mg of the active substance orlistat, which acts as a lipase inhibitor.
XENICAL® is a weight loss medication that targets the absorption of fat in your body rather than suppressing your appetite. It is useful for long term use and has been shown to be effective for 1-2 years. Dietary fats are inhibited from being absorbed and this allows about 30% of the fat eaten in the meal to pass through the gut undigested. This helps you to reduce and maintain your weight, as well as to minimize any weight regain.
Xenical is taken with each meal (three times daily). Your daily fat intake should be divided equally between these three meals so you will benefit from Xenical's actions. Your medicine should be swallowed with water.
Effective Dose: 3 tabs per day
Xenical capsules. Each Xenical capsule contains 120 mg. orlistat. Xenical comes in packs of 84 capsules and is manufactured by Roche.
Common uses and directions for Xenical
Xenical achieves weight loss by using the existing fat from the body. By taking Xenical with each meal (3 times daily), Xenical allows one third of the fat to pass through the body undigested, aiding in weight loss.
Health problems, such as high cholesterol, high blood pressure and diabetes, have improved with extended use of Xenical diet pills. Xenical should still be taken with a low fat diet program and fat intake should be split evenly between the 3 daily meals. With regular use, Xenical diet pills help achieve weight loss, maintain your weight loss and minimize any weight regain.
Xenical has a greater success of weight loss when accompanied by a reduced calorie diet plan with no more than 30% of calories from fat. By not reducing your fat intake while taking Xenical, a greater chance of unwanted side effects such as oily discharge may occur.
The National Institute of Clinical Excellence (NICE) has recommended that Xenical is used under the following conditions:
Individuals with a body mass index (BMI) of 30 kg/m2 or more.
Individuals who have lost at least 2.5 kg body weight by dietary control and increased physical activity in the preceding month.
Individuals between the ages of 18 and 75.
Discontinue use of Xenical if weight loss is less than 5% after the first 12 weeks.
Discontinue use of Xenical beyond 3 months only if weight loss is greater than 5% from the start of treatment.
Discontinue use of Xenical beyond 6 months only if weight loss is greater than 10% from the start of treatment.
Use of Xenical should not continue beyond 1 year and never beyond 2 years.
Xenical (Orlistat) additional information:
Xenical contains the active ingredient orlistat, for oral administration. Each Xenical capsule contains 120 mg. orlistat.
Xenical is indicated for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Xenical is also indicated to reduce the risk for weight regain after prior weight loss.
Take Xenical by mouth, generally three times daily during (or up to one hour after) each main meal that contains fat. The daily intake of fat, protein and carbohydrate should be evenly spread over three main meals. If a meal is occasionally missed or contains no fat, skip that dose of Xenical. Because Xenical can interfere with absorption of fat-soluble vitamins (e.g., A,D,E,K), a daily multivitamin supplement containing these nutrients is recommended. Take the multivitamin at least 2 hours before or 2 hours after Xenical (e.g., at bedtime). The effects of Xenical may begin as soon as 1-2 days after treatment begins; noticeable weight loss will take longer.
If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Gastrointestinal events may increase when Xenical is taken with a diet high in fat (>30% total daily calories from fat).
There are no adequate and well-controlled studies of Xenical in pregnant women. Xenical is not recommended for use during pregnancy.
It is not known if orlistat is secreted in human milk. Therefore, Xenical should not be taken by nursing women.
The safety and efficacy of Xenical in pediatric patients have not been established.
Some individuals may develop increased levels of urinary oxalate following treatment with Xenical. Caution should be exercised while using Xenical by individuals with a history of hyperoxaluria or calcium oxalate nephrolithiasis.
Weight-loss induction by Xenical may be accompanied by improved metabolic control in diabetics, which might require a reduction in dose of oral hypoglycemic medication or insulin.
Xenical, possible side effects
Xenical may cause some side effects that are usually mild to moderate and decrease after the first week of the treatment. The most common side effects are fatty/oily stool, oily spotting, intestinal gas with discharge, bowel movement urgency, poor bowel control, or headaches may occur. If these effects persist or worsen, notify your doctor promptly. Intestinal side effects (e.g., oily stool) may increase in intensity if you exceed your daily dietary fat allowance. If you notice other effects not listed above, contact your doctor.
Should a significant overdose of Xenical occur, it is recommended that the individual be observed for 24 hours. Systemic effects attributable to the lipase-inhibiting properties of orlistat should be rapidly reversible.
Xenical, additional information
Keep Xenical in a tightly closed container and out of reach of children. Store Xenical at room temperature and away from excess heat and moisture (not in the bathroom).
The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of Xenical is safe, appropriate, or effective for you. Consult your healthcare professional before using Xenical.